Course Details in 2024/25 Session

Module Title	Cancer and Stratified Medicine
School	Cancer Studies
Department	Inst of Cancer / Genomic Sci
Module Code	02 27785
Module Lead	M.Taylor & A.Beggs
Level	Intermediate Level
Credits	20
Semester	Semester 2
Pre-requisites
Co-requisites
Restrictions	It is a requirement that students achieve a mark of at least 35% in their summative exam
Contact Hours	Lecture-29 hours Tutorial-7 hours Supervised time in studio/workshop-2 hours Guided independent study-162 hours Total: 200 hours
Exclusions
Description	The aim of the module is to provide students with an up to date knowledge of what cancer is, what the risk factors are for different cancers and the cellular events that result in cancer development. The molecular origin of different cancer types will be described in order to show how this knowledge contributes to devising treatments for cancer. The broad principles of the treatment of cancer will be described with emphasis on how information on individual tumours can be used to stratify them into different categories so that the most efficacious treatment can be used for that particular tumour.
Learning Outcomes	By the end of the module students should be able to: Demonstrate knowledge of the characteristics of individual tumour cells compared with normal cells. Demonstrate an understanding of the characteristics of malignant tumours including genetic variation, self sufficiency in growth signals, insensitivity to growth supressing signals, resistance to apoptosis and limitless replicative growth in cancer growth. Demonstrate an understanding of the characteristics of malignant tumours including the role of invasion, metastasis and angiogenesis in tumour development. Demonstrate an understanding of environmental factors including, cigarette smoking, diet and viruses in tumour development. Demonstrate an understanding of the concept of cancer as a genetic disorder at the cellular level. Demonstrate an understanding of the roles of tumour suppressor gene, oncogenes and DNA damage response genes in cancer development. Demonstrate a basic knowledge of the importance of the immune response in cancer control. Demonstrate an understanding of the approaches to screening for and prevention of cancer. Demonstrate a basic knowledge of the approaches to treating different cancers. Demonstrate an understanding of the rationale for drug trials. Demonstrate an understanding of the necessity for an integrated approach to treatment based on biology of the tumour and stratification of the tumour type into subgroups with common biological features.
Assessment	27785-01 : Overall Module Mark : Mixed (100%)
Assessment Methods & Exceptions	Assessments: Module assessment will consist of a combination of a written unseen paper and one in course assessment. 2 hour written unseen paper: 50% In Course Assessment: 50% Group work - In-course assessment consists of a group report. Each group will develop an Experimental strategy on a given specific research question within the field of cancer and stratified medicine. The group will complete a report template for the in course assessment and a peer assessment component will be integrated to calculate the final mark to reflect group participation. Reassessment: Academic failure: If a student fails the module then they will be required to repeat the failed components only. If the failed component is the In course assessment the student will have to submit an individual report on an experimental design to an assigned question. Failure to submit: Submission of coursework is compulsory for the programme. Students are advised that failure to submit without justifiable reason could result in failure of the module. Students will be required to submit outstanding work to meet the module outcomes.
Other	None
Reading List