Course Details in 2024/25 Session

Module Title	LI Orthopaedic Biomaterials
School	Institute of Clinical Sciences
Department	Dentistry
Module Code	02 29560
Module Lead	Rachel Sammons and Michael Hofmann
Level	Intermediate Level
Credits	20
Semester	Semester 1
Pre-requisites
Co-requisites
Restrictions	None
Contact Hours	Lecture-23 hours Tutorial-13 hours Demonstration-2 hours Practical Classes and workshops-6 hours Guided independent study-156 hours Total: 200 hours
Exclusions
Description	This module covers the composition, development, mineralisation, maintenance and remodelling of bone, including the roles of bone cells and proteins associated with ossification. This information is developed to encompass fracture healing, hormonal control of calcium regulation and selected major bone diseases and disorders. The structure and function of joints of the lower and upper limbs, associated blood supply and neuromuscular systems are also covered. The impact of material characteristics and performance on the clinical use of biomaterials in orthopaedic surgery are reviewed through consideration of a range of orthopaedic interventions. The design requirements for artificial hips, knees, elbows and shoulders are introduced and their effectiveness is discussed in relationship to the need for and causes of revision surgery. The mechanical testing practical provides hands-on experience in sample preparation and evaluation of bone and implant material mechanical properties.
Learning Outcomes	By the end of the module students should be able to: Describe the structure and composition of healthy bone; Describe the roles of osteoblasts, osteocytes and osteoclasts Explain how mineralisation occurs and is regulated by non-collagenous proteins Demonstrate an understanding of the role of bone morphogenetic proteins in bone development Describe the role of the endocrine system in calcium regulation Describe the differences between endochondral and intramembranous ossification Explain the theory of mechanotransduction with reference to the impact of changes in stress on bone caused by implants Discuss how implant surface topography can influence bone cell behaviour7 Describe the Anatomy of the upper and lower limbs with reference to biomaterials for repair and replacement Produce a design specification for artificial joints Demonstrate an understanding of the Impact of metals/ceramics and polymers on body; Demonstrate an understanding of why wear occurs in artificial joints Discuss the Pros and cons of treatment options in specific applications Demonstrate an understanding of the use of lifetables to predict and review clinical performance; Critically review new intervention approaches; Explain why revision of artificial joints may be needed; Understand the concept of mechanical testing;
Assessment	29560-01 : Examination : Exam (Centrally Timetabled) - Written Unseen (50%) 29560-02 : Coursework - 1000 word case study : Coursework (25%) 29560-07 : Group presentation : Coursework (25%)
Assessment Methods & Exceptions	Assessment Examination (50%) 2h unseen SAQ Coursework (50%) comprising:- Case study / essay (25%). The pass mark for the module is 40% and students must achieve a minimum of 35% in both examination and coursework components to pass the module.Reassessment Opportunity to resit the examination in the supplementary examination period. If a student achieves an overall coursework mark of <35% the failed element(s) or an agreed alternative must be repeated and resubmitted/presented in or before the supplementary examination period.
Other
Reading List