Course Details in 2025/26 Session

Module Title	LH Pathophysiology for Nurses
School	Institute of Clinical Sciences
Department	Nursing and Midwifery
Module Code	02 29887
Module Lead	Richard Breakwell
Level	Honours Level
Credits	20
Semester	Semester 1
Pre-requisites
Co-requisites
Restrictions	Met requirements for enrolment on the Master of Nursing programme or is registered nurse (standalone module) It is an NMC requirement that all students have an enhanced Disclosure and Barring Service (DBS) check prior to starting the programme Self- declaration of continued health and character is completed at the start of every academic year.
Contact Hours	Lecture-16 hours Seminar-12 hours Tutorial-2 hours Practical Classes and workshops-6 hours Guided independent study-164 hours Total: 200 hours
Exclusions
Description	Module aim: This module aims to equip student nurses with complimentary underpinning pathophysiological knowledge to enhance nursing practice and to support the development of future clinical assessment and diagnostic knowledge at Level M. Content: Students will review the genome and genetic variations: chromosome number and structure, changes in DNA sequence and copy number variation, genes and protein function, polymorphism. Multifactorial genetic conditions, single-gene conditions, chromosomal conditions, mitochondrial conditions. Cellular biology and the processes of inflammatory/infectious responses, cancer and cancerous metastases. The study of pathophysiological variation in all body systems. When exploring systems, students will consider these pathophysiological variations across the lifespan and provide explanation and rationale for the use of common diagnostic mechanisms and measures. Strategies: Study of the cell, cellular changes and genomics will be developed through a lecture series with directed pre and post online activities and reading and workshop activities. Through directed group seminar work students will explore in depth patho-physiological changes in a given system and will present this learning to the whole group. Seminars will be recorded via lecture capture software (Panopto) and will include formative feedback made available to the whole group.
Learning Outcomes	By the end of the module students should be able to: Demonstrate in depth understanding of the mechanisms leading to cell changes, cell injury and cell death (Examination) Explain how alterations to the genome influence individual health and pathophysiological processes. (Examination) Compare variations in pathophysiological processes across the human lifespan (Examination) Synthesise and communicate complex ideas and pathophysiological processes of common and acute conditions experienced by people. (Examination)
Assessment	29887-01 : Online Open Book Exam : Exam (School Arranged) - Open Book (80%) 29887-02 : Online MCQ x4 : Exam (School Arranged) - Open Book (20%)
Assessment Methods & Exceptions	Assessment: (100%) 3-hour examination (LO 21.1-21.4) Reassessment: Student will re-sit any failed component(s): Exam: re-sit exam
Other
Reading List	Blows, W.T. (2012) The biological basis of clinical observations. 2nd edn. Oxon: Routledge Lazenby, R.B. (2010) Handbook of Pathophysiology. 4th edn. Philadelphia: Lippincott Williams and Wilkins. McCance, K and Huether, S.E (2014) Pathophsyiology: The biologic basis for disease in adults and children 7th edition, Mosby Knight, J.C (2015) Human Genetic Diversity: Functional Consequences for Health and Disease Oxford University Press