Course Details in 2026/27 Session

Module Title	LH Neurotrauma and disease: Degeneration and Regeneration
School	Inst of Inflammation / Ageing
Department	Inst of Inflammation / Ageing
Module Code	02 33933
Module Lead	Module lead: Dr D Fulton Deputy lead : Dr Z Ahmed
Level	Honours Level
Credits	40
Semester	Semester 1
Pre-requisites
Co-requisites
Restrictions	It is a requirement that students achieve a mark of at least 35% in their summative exam
Contact Hours	Lecture-23 hours Tutorial-26 hours Practical Classes and workshops-24 hours Guided independent study-327 hours Total: 400 hours
Exclusions
Description	The course, delivered by front-line research scientists, will enable students to gain a deeper understanding of: 1) the molecular and integrative mechanisms involved in the response of the nervous system to trauma and disease, and the processes involved in degeneration and regeneration; the importance and value of experimental models. The first part of this module covers aspects of electrical and ion channel signalling in health and disease and mechanisms of cell death. The module then considers the molecular and cellular aspects of CNS trauma, degeneration and regeneration in traumatic brain, spinal cord and ocular injuries. The module then focuses on the neurobiology of pain and the control of motor function. Finally it discusses the fundamental concepts of CNS barriers and current CNS therapeutic strategies. Two in-course assessments are included: (1) A written experimental data handling practical where students have a choice of cellular imaging and Western blot data sets that they must organise, analyse and interpret before producing an assessed report. (2) A poster presentation providing a critical analysis of a relevant topic of their choosing that must synthesise findings from at least two studies. This course encourages critical discussion of scientific literature and as such includes a relevant journal club at the end of each week of the course.
Learning Outcomes	By the end of the module students should be able to: Demonstrate knowledge of the cellular and molecular mechanisms involved in nervous system injury, disease and regeneration, and of the current and future therapeutic approaches that can be used to encourage this repair Demonstrate knowledge of the experimental approaches used in the study of nervous system injury, disease and regeneration Demonstrate the ability to critically appraise and evaluate the current scientific literature in the context of nervous system injury, disease and regeneration Demonstrate the capacity to develop and present logical arguments supported by evidence from relevant scientific literature
Assessment	33933-01 : Overall Module Mark : Mixed (100%)
Assessment Methods & Exceptions	The module is assessed by a combination of a 3 hour written examination (50%) and course work (50%) - experimental data interpretation - practical write up Reassessment: Academic failure: If a student fails the module then they will be required to repeat the failed components only. Failure to submit: Submission of coursework is compulsory for the programme. Students are advised that failure to submit without justifiable reason could result in failure of the module. Students will be required to submit outstanding work to meet the module outcomes.
Other
Reading List