Course Details in 2027/28 Session

Module Title	LM Tumour Virology
School	Inst of Immunol + Immunoth
Department	Inst of Immunol + Immunoth
Module Code	02 38643
Module Lead	Dr Claire Shannon-Lowe and Prof Jo Parish
Level	Masters Level
Credits	20
Semester	Semester 1
Pre-requisites	Immunity and Infection - (02 27786) Cancer and Stratified Medicine - (02 27785)
Co-requisites
Restrictions	None
Contact Hours	Lecture-14 hours Seminar-3 hours Tutorial-4 hours Practical Classes and workshops-14 hours Guided independent study-165 hours Total: 200 hours
Exclusions
Description	This module will give an overview of how viruses intersect with hallmarks of cancer to drive tumorigenesis. The students will be able to understand the differences between direct carcinogens and indirect carcinogens. Attention will be focused on (i) the molecular mechanisms of the direct viral carcinogens and (ii) the factors essential to cooperate with viruses that function as indirect carcinogens, including understanding how viruses mimic somatic cellular mutations to drive carcinogenesis. Additionally, the module will focus on viral tumour immunology and how viruses manipulate the immune response. An overview of therapeutic approaches to target the virus-associated cancers will be given. The module contains a variety of integrated learning environments, including lectures and tutorials. Laboratory practicals will provide a better understanding of techniques that are used in tumour virology research and will generate data that they will learn to analyse, interpret and write-up in the format of a paper.
Learning Outcomes	By the end of the module students should be able to: Demonstrate a detailed understanding of how viruses contribute to the hallmarks of cancer and their molecular mechanisms of carcinogenesis. Demonstrate an understanding of the rationale for the therapeutic approaches to treating virus-associated cancers Demonstrate a synthesis of the different concepts to evaluate if a virus is a direct or an indirect carcinogen Demonstrate an ability to critically appraise published articles and present their arguments clearly and logically during journal clubs Analyse, interpret and evaluate laboratory data; demonstrate synthesis of understanding how the results relate to virus-associated tumorigenesis and present the results in the form of a paper.
Assessment	38643-01 : Overall Module Mark : Mixed (100%)
Assessment Methods & Exceptions	Assessment: The module is assessed by a combination of a written examination and course work: Examination; Students must answer 2 from 4 DIQ/Essay in a 2 hour period. 50% (Semester 1) Course Work; Laboratory practicals using research techniques; analysis and interpretation of data generated; ewrite-up in the format of a short paper. 50% (Semester 1) It is a requirement that students achieve a mark of at least 45% in their summative exam or coursework. Overall Pass mark for the module is 50%. Reassessment: Failure to submit: Submission of coursework is compulsory for the programme.  Students are advised that failure to submit without justifiable reason could result in failure of the module.  Students will be required to submit outstanding work to meet the module outcomes. Student will be required to repeat any failed component of the module In the event of failure in a module students will have a further opportunity to retrieve lost credit by resubmission or resit of ICA and/or exam with the mark capped at the pass mark at the next available opportunity.
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