Cardiovascular disease is the leading cause of death and major cause of disability worldwide. This module will introduce students to multiple aspects of contemporary practice in cardiology and the underpinning basic science and clinical research, showcasing the research strengths of the Institute of Cardiovascular Sciences. The teaching on this module builds on that from the early years of medical degree and encompasses a combination of basic science and clinical application to give a state-of-the-art view of cardiovascular medicine. It will cover both normal heart function and a range of cardiac diseases, including molecular pathology, imaging, diagnosis and treatment. This module will demonstrate how the use of basic science and pre-clinical models deepens our understanding of the pathophysiology of heart disease and enables novel therapeutic strategies to be developed. Looking to the future, it will explore how clinical trial design, advances in health data science and biomarker discovery is shaping risk stratification and improving care in cardiovascular disease.
Learning Outcomes
By the end of the module students should be able to:
Describe and explain current knowledge in the field of cardiovascular biology, including regulation of heart rhythm and heart physiology.
Demonstrate knowledge of principles in disease in selected examples of arrhythmias, cardiomyopathies and congenital heart disease, including their molecular pathophysiology, diagnosis and general treatment strategies.
Explain the pathogenesis of atherosclerosis and thrombotic cardiovascular diseases, heart failure, sudden death and atrial fibrillation, and discuss both acute and longer term treatments of these major diseases. Discuss risk factors of heart disease, how they contribute to the pathogenesis of the disease and are managed clinically.
With reference to the scientific literature, discuss the different domains of cardiovascular research from molecular discovery to patient benefit.
Discuss and evaluate the impact of biomarker discovery, clinical trial design and advances in digital cardiology in the understanding, detection and management of cardiovascular disease.
Assessment
39083-01 : Overall Module Mark : Mixed (100%)
Assessment Methods & Exceptions
Assessment:
End of Module Exam 3 hours; 3 xEssays (50%) ICA Presentation (50%)
Reassessment:
All failed components can be resubmitted at the next available opportunity.