Course Details in 2024/25 Session

Module Title	LI Health Sciences 2
School	Institute of Clinical Sciences
Department	Pharmacy
Module Code	01 39108
Module Lead	Anisa Choudhary
Level	Intermediate Level
Credits	40
Semester	Full Term
Pre-requisites	Basic Life Support - (01 27326) LC Health Sciences 1 - (01 39101) LC Science of Medicines 1 - (01 39102) LC Professional Experience Placements 1 - (01 39106) LC Applied Pharmacy Practice 1 - (01 39100) LC Portfolio 1 - (01 39103)
Co-requisites
Restrictions	Students are required to achieve a minimum module mark of 50%, and a minimum of 40% in each component of the module (course work and examinations).
Contact Hours	Lecture-77 hours Tutorial-32 hours Practical Classes and workshops-10 hours Guided independent study-281 hours Total: 400 hours
Exclusions
Description	This module will be delivered in Year 2, commencing in semester 1 and spanning the academic year. The module will provide essential knowledge of the structure and function of the kidney highlighting its significance in terms of homeostasis and as a major excretory organ of products of metabolism. Renal tract anatomy and normal physiology will be covered. The causes, consequences and management of renal dysfunction will be discussed. The normal physiological operation and anatomy of the cardiovascular system and respiratory system will be covered, and the effects of pathological processes on these systems. Students will be introduced to haemopoiesis and anaemias and how renal, gastrointestinal, central nervous and immune system functions interact with red cell production and oxygen delivery to tissues. The associated processes of thrombosis will be explored, along with their relationship to the development of disease. The physiology and anatomy of the central nervous system will be related to key examples of major disease processes, including Parkinson’s, epilepsy, and dementia. Psychosis and depression will be used as early examples of mental illness, in preparation for more dedicated mental health teaching later in Year 3. The mechanisms of pain and the pharmacological basis of its amelioration will be described. The normal physiological changes related to age, pregnancy and breastfeeding will also be explored in relation to the significance for altered pharmacodynamics and pharmacokinetics. Finally, the module will build on Year 1 immunology teaching, applying this to the principles of vaccination, diagnostics, and therapeutics as a grounding for further exploration of these topics in relation in Year 3. Students will conduct diagnostic procedures aligned to the topics taught (e.g. electrocardiograms and spirometry). Throughout this module the pharmacology and therapeutics of the treatment and prevention of disease will be taught in the context of both individual patient therapeutics and population level. Prior learning in evidence-based medicine from other modules will be integrated and applied in this context, in terms of the monitoring of medicines, management of adverse effects therapeutic considerations in practice. The appraisal of reputable and evidence-based information will be approached so that students continue to develop the skills to provide appropriate advice and information to empower people to engage in shared decision-making about health and wellbeing and adapt this to their needs.
Learning Outcomes	By the end of the module students should be able to: Apply prior learning and integrate it with the new learning content of this module. Describe the major functions of the blood cells and interpret results of basic haematology tests in relation to common haematological disease. Demonstrate an understanding of haemostasis and thrombosis, and common pharmacological interventions. Describe innate and adaptive immune responses and how immunological techniques can help in diagnosis, prevention, management and monitoring of disease. Describe the anatomy of the renal and urinary system including the underlying physiological process and its role in maintaining homeostasis. Interpret biochemical tests used to monitor renal function. Describe how transport properties of the nephron relate to excretory functions and explain how this can be modulated by administration of diuretics and other drugs. Explain the major underlying causes and classification of acute and chronic kidney disease and outline the management of the complications of these conditions including altered drug pharmacodynamics Discuss the practical management of drug interactions with reference to their pharmacokinetics and pharmacodynamic mechanisms and in relation to differing patient susceptibilities. Interpret information from clinical case scenarios to identify different classes of adverse drug reaction and describe the management and reporting processes. Discuss the significant factors affecting the pharmacokinetics and pharmacodynamics of drugs in neonates, paediatric, adolescent, older adults, and during pregnancy and breast feeding, linking these to choice of medicines in these groups. Describe the anatomy of the cardiovascular system, respiratory system, and central nervous systems and explain their functions and processes. Discuss the pathology, epidemiology, risk factors and treatment of diseases of the cardiovascular, respiratory, and central nervous systems. Explain the pharmacology related to problems of the respiratory, cardiovascular, and central nervous systems. Discuss common infections of the respiratory, cardiovascular, and central nervous systems, and evidence-based treatment strategies for these. Explain the biochemistry and physiology of cholesterol and lipoprotein metabolism and discuss the pharmacological interventions for dyslipidaemia. Critically appraise the evidence base for a therapeutic drug selection. Collect and interpret respiratory and cardiovascular physiological readings. Explore the pharmacokinetic considerations of the therapeutics agents used in the treatment of the cardiovascular, respiratory, and central nervous system.
Assessment	39108-01 : Therapeutic Group Presentation (non-clinical) : Presentation (15%) 39108-02 : Webfolio (non-clinical) : Coursework (25%) 39108-03 : End of Year Exam (non-clinical) : Exam (Centrally timetabled) - Computer based (60%)
Assessment Methods & Exceptions	Assessment: Coursework: Group oral presentation (15%): therapeutic area focus (non-clinical Digital asset (25%): webfolio (non-clinical) Examinations: On-campus timed closed book: MCQ/SAQ 3-hour (60%) (non-clinical) Reassessment: Students who fail to achieve a minimum module mark of 50% will be reassessed in every element (examination and coursework) in which they achieved less than 50%. This will take place in the supplementary exam period. Group work: upon submission of group work, students are requested to declare if any students did not contribute equally to the assessment. If unequal contribution is declared, each student is asked to independently complete a 'Self and peer assessment form', scoring different aspects of contribution and teamwork. Individual student marks can be reduced based on their contribution. A failure of a single student would require re-submission of an alternative aligned assessment, appropriately weighted to an individual assessment.
Other
Reading List