The is the first module on the MSc Clinical Oncology and MRes Cancer Sciences programmes and covers the underpinning knowledge on how “normal” cells cycle and repair themselves, and cutting edge teaching on how cancer cells develop as a result of mutational, environmental and viral pressures. The module teaching will reflect the most up-to-date knowledge in the field of cancer biology. Students will be expected to “read-around” these areas to consolidate their understanding. Students will also have the opportunity to observe laboratory techniques used in the study of oncology. Specific papers will be recommended for students to study to increase their understanding of these research techniques. Finally students will undertake an in depth study of a chosen aspect of cancer cell biology to produce a 3000 word assignment. This is a core requirement for both programmes.
Learning Outcomes
By the end of the module students should be able to:
Explain our current understanding of the mechanisms that regulate and control normal cell growth and critically discuss how these processes are altered in cancer cells
Provide an in-depth explanation of how the body identifies and destroys cancer cells and how this information is currently being used to develop anti-cancer therapies
Describe in detail the genetic structures of cells and the mechanism of inheritance
Critically discuss our current understanding of how human genes contribute to the development of cancer
Critically discuss the impact of the environment (including infections with viruses) on the development of human cancers
Provide an in-depth explanation of the mechanisms that lead cancer cells to metastasise
Describe the molecular detail of the various DNA repair processes and how errors in these pathways can lead to cancer
Describe the sorts of laboratory research techniques that are used for the study of oncogenesis
Assessment
00146-01 : 3000 word essay : Coursework (100%)
Assessment Methods & Exceptions
Assessment 3000 word written assignment- Students select one question from 3 options. The questions are open/ discursive questions that require students to demonstrate a wide knowledge of the field and evaluate the evidence base. (60% of the module mark)
1 h Multiple choice questions examination (40% of the module mark)
Student must attempt both components
Reassessment If a student fails the module they will be required to repeat the failed component only.
Students failing the essay will be required to re-write the assignment based in the feedback provided.
Failure to submit: Submission of coursework is compulsory. Students are advised that failure to submit without justification could result in failure of the module. Students will be required to submit outstanding work to meet the module outcomes. Failure to attend the exam will mean that the student has failed that component and will be required to re-sit it.
