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Module Title Molecular and Integrative Pharmacology: From Molecules To Man
SchoolInstitute of Clinical Sciences
Department Pharmacy
Module Code 02 20311
Module Lead Dr M Keen and Dr AJ Cooper
Level Honours Level
Credits 30
Semester Semester 1
Pre-requisites
Co-requisites
Restrictions Chemistry with Pharmacology
Contact Hours Lecture-23 hours
Seminar-4 hours
Tutorial-5 hours
Practical Classes and workshops-19 hours
Guided independent study-249 hours
Total: 300 hours
Exclusions
Description This module aims to develop the students understanding of both modern receptor pharmacology and of the need to use tissues and whole animals in drug research and development. There is a particular emphasis on the experimental approaches used and the interpretation of experimental evidence.
Learning Outcomes By the end of the module the student should be able to:
  • recognise the importance of studying the effects of drugs at the molecular, intact tissue and whole body levels
  • distinguish the structure and function of some of the major classes of receptors
  • discuss how the signals from various receptor systems may be integrated at a cellular level to produce a co-ordinated response
  • illustrate the ways in which pharmacokinetics, adaptive reflexes and homeostatic mechanisms may modify the effects of drugs in different experimental systems
  • document the problems involved in developing animal paradigms of human disease states
  • state the implications of the regulatory processes which control the introduction of new drugs and comprehend the Home Office Regulations regarding the use of animals in research
  • compare the experimental techniques involved in current research in molecular pharmacology and the variety of methods which may be employed to study the action of drugs in vivo
Assessment 20311-01 : Overall Module Mark : Mixed (100%)
Assessment Methods & Exceptions The module is assessed by a combination of a written examination (3 essay questions) and course work
Examination: 75% (Semester 2)
Course Work: 25% (Semester 1)

The course work component will include the following:
Essays: 40%
Practical workbooks: 40%
Student led seminar : 20%
Other Introductory Learning Resources - Pharmacology (Level 2)
Reading List Up-to-date review articles and research papers which are recommended to students at the end of each lecture.