It will include a coverage of the technological progress:
History: Sanger sequencing through array technologies
Next generation Sequencing
Advanced library construction procedures for specialized assays (e.g. ChIP, DNase, ATAC, HiC, eCLIP)
This module will as well address specific fields of
Classical Genetics
Population Genetics
Cancer Genomics
It will involved a biological, technological and analytical dimension to help the student design the best experiment with the appropriate data type and enable its analysis with the latest state of the art approaches.
Learning Outcomes
By the end of the module students should be able to:
Understand the biological interpretation of the various *omics fields, especially DNA, RNA and Methylation based.
Understand the various technologies available to measure the various type of information from Sanger sequencing, micro-array, Mass-Spectrometry to Next Generation sequencing
Analyse the various types of data generated in the field both with command line and web interface such as Galaxy
Integrate the various type of data to understand the biological implication of the results
Deal with the complexity of information available to enable the integration of diverse data types
Assessment
29780-02 : Group Presentation : Presentation (40%)
29780-04 : Examination : Exam (Centrally Timetabled) - Written Unseen (60%)
Assessment Methods & Exceptions
Assessment:
• 3 hours examination as Short Answer Questions 60% • 30 min Group Presentation 40%
Reassessment:
If a student fails the module then they will be required to repeat the failed components only.
