Course Details in

Module Title	Organic Chemistry II
School	Chemistry
Department	Chemistry
Module Code	03 10854
Module Lead	DR. Peacock
Level	Honours Level
Credits	10
Semester	Semester 2
Pre-requisites
Co-requisites	Organic Chemistry I - (03 10853)
Restrictions	The module is available to all students on the above programmes and is offered to suitably qualified occasional students. For the latter, enrolment is determined on a case-by-case basis using academic transcripts.
Contact Hours	Lecture-28 hours Practical Classes and workshops-3 hours Total: 31 hours
Exclusions
Description	This level 3 module utilises the principles and concepts developed through pre-requisite modules (Synthesis and Mechanism I and II). The module covers aspects of supramolecular chemistry, stereoselective synthesis and heterocyclic chemistry.
Learning Outcomes	By the end of the module students should be able to: Demonstrate an understanding of the (advanced) principles and concepts associated with the material delivered in each area; Apply their acquired knowledge to the solution of relevant problems; Describe the different types of binding interactions and complexes found in supramolecular chemistry; Discuss how cation receptors can be designed and understand what factors govern binding strength and selectivity; Describe the different types of receptors for anions and neutral molecules and discuss the important factors that govern receptor design; Describe the different types of interlocked structure and the variety of approaches used in their synthesis; Recall and discuss multiple methods for obtaining the products of reactions that yield chiral molecules in enantioenriched form; Recall and explain examples of the use of chiral auxiliaries; Recall and explain examples of the use of chiral catalysts; Recall and explain the concept of catalytic kinetic resolution; Understand the concepts behind stereoselective oxidation methods; Compare and contrast Lewis acid catalysis and organocatalysis; Design the synthesis of chiral molecules including key functional groups; Define heteroaromaticity; Describe the bonding and hybridization of heteroaromatic compounds: pyridines, pyrroles (and related);quinolines (and related); indoles; heterocycles with more than one heteroatom; Explain the relative reactivity of each of these compounds toward electrophiles, nucleophiles and bases using mesomeric and inductive arguments (with the aid of diagrams); Predict the reaction outcome and selectivity patterns observed when the heteroaromatic compounds are treated with of a range of electrophiles, nucleophiles, acids and bases; Predict the impact of substitution on the reactivity of the heteroaromatic motifs; Identify starting materials, reaction conditions and mechanisms involved in the preparation of substituted heteroaromatic compounds; Design and discuss synthetic approaches to a range of medicinally active molecules based on their understanding of fundamental reactivity concepts behind these molecules.
Assessment	10854-01 : Exam : Exam (Centrally Timetabled) - Written Seen (100%)
Assessment Methods & Exceptions	Formal Written Unseen Examination - 100 % An end of session examination contributes 100 % to the overall module mark. The examination is 2 hours in duration and is closed book. The exam assessment for this module is linked to the module title: Organic Chemistry I (03 10853) Reassessment: No opportunity for reassessment
Other	none
Reading List