This course concentrates on the dramatic advances that have taken place in reproductive and developmental biology in the last 20 years. These include the introduction of IVF and ICSI technology, in vitro storage & maturation of reproductive tissues and gametes, a functional genetic understanding of developmental processes and their relation to human congenital disorders and the therapeutic use of stem cells. The emphasis of this module is on human reproduction and development as it relates to human disease process and the possible treatment of patients. However, data from animal studies is presented to aid understanding. In addition to the physiological, molecular and biochemical basis of the subject, students will get a solid grounding in the ethical and moral challenges of the field.
Topics covered:
The production of sperm and eggs (gametogenesis)
Gamete maturation and transport
Fertilisation
Early embryo development
Contraception
Pre-implantation embryo screening
Infertility
Reproductive technologies and controversies
Ethical issues and regulatory issues associated with assisted and applied reproduction
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