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Module Title
LH Molecular and Cellular Immunology
School
School of Bioscience
Department
School of Biosciences
Module Code
03 21894
Module Lead
Dr Futterer
Level
Honours Level
Credits
20
Semester
Semester 2
Pre-requisites
Co-requisites
Restrictions
None
Contact Hours
Lecture-18 hours
Tutorial-5 hours
Project supervision-5 hours
Supervised time in studio/workshop-5 hours
Guided independent study-167 hours Total: 200 hours
Exclusions
Description
The emphasis of this module is on how the immune system works, with a focus on molecular and cellular aspects. The main areas covered may include (but are not limited to): (i) the evolution of the immune system, (ii) innate immunity and the role of phagocytes, inflammatory responses and intracellular killing mechanisms, (iii) adaptive immunity and the role of B cells, T cell subsets, antigen presenting cells, interleukins and cell surface receptors, (iv) immunity and infection killer cells and killing mechanisms, (iv) the structures, signalling pathways, cell biology and interactions involved in antigen recognition, T and B cell responses, antibody-antigen complexes, (v) immunological disorders, including hypersensitivity, and autoimmune diseases and transplantation, (vi) vaccines and therapeutic antibodies.
The aim of the module is to develop a knowledge in immunology and the methods used to investigate the subject. This will be achieved by a combination of (i) lectures, (ii) data interpretation sessions, (iii) practicals on leukocyte identification using microscopy and (v) student reading material available on e-journals and in the library.
Learning Outcomes
By the end of the module the student should be able to:
Demonstrate a body of knowledge of physiological, cellular and molecular features of the immune systems in humans and other organisms;
Link molecular and cellular components of the immune system to physiological outcomes in protection against infection, and autoimmune conditions;
Interpret data based on experiments in molecular and cellular immunology in terms of cellular and molecular features of the immune system;
Present a topic in molecular and cellular immunology in the form of a critical evaluation of a controversy in immunology
Understand through practical training how cell staining and microscopy can be used to identify cells of the immune system in blood smears.
Assessment
21894-04 : Controversies Assignment with Data Interpretation : Coursework (50%)
21894-05 : Examination : Exam (Centrally timetabled) - Computer based (50%)
Assessment Methods & Exceptions
Assessment: In-course assessment (50%) consists of a 1000 word critical analysis of a controversy in immunology. The examination consists of an open book examination (50%) during the main examination period (May/June)
Reassessment: Students will take the supplementary exam for 100% of the module.