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Module Title LI Proteins and Enzymes
SchoolSchool of Bioscience
Department School of Biosciences
Module Code 03 23326
Module Lead Dr Michael Baker
Level Intermediate Level
Credits 20
Semester Semester 2
Pre-requisites LC Fundamentals of Biochemistry - (03 28776) LC Physical Biochemistry - (03 22652)
Co-requisites
Restrictions None
Contact Hours Lecture-28 hours
Seminar-3 hours
Tutorial-1 hours
Practical Classes and workshops-18 hours
Guided independent study-150 hours
Total: 200 hours
Exclusions
Description Assessments: 2 hour examination - 65% comprising essay questions and short-answer questions. This may include some data-handling problems. Continuous assessment 35% comprising:
  • Practical write-up 10%
  • Data-handling test 20%
  • Molecular graphics 5%
    Reassessment: Supplementary examinationResit mark for the module is based solely on exam performance. Continuous assessment marks are not counted. Resit examinations will cover the whole course, i.e. theoretical aspects and practical aspects.
    • Learning Outcomes By the end of the module the student should be able to:
    • Explain how the amino acid sequence of a protein is related to its structure and hence to its function; including simple ideas of protein evolution and common secondary structure motifs;
    • Describe some common protein folds and structural motifs, and relate these to the functional roles of motifs, and how the structures are stabilised.;
    • Evaluate techniques used to determine the primary , secondary, tertiary and quarternary structures of proteins and explain the biophysical principles behind these techniques;
    • Discuss the mechanisms underlying the catalysis of reactions by certain enzymes and methods used to determine enzyme rates and mechanisms;
    • Analyse and interpret numerical data of ligand binding, UV spectroscopy, pH and enzyme kinetics, including use of SigmaPlot;
    • Download, display and examine protein structure from the RSC protein database.
    Assessment 23326-01 : Continuous Assessment : Coursework (50%)
    23326-02 : Sessional Examination : Exam (Centrally Timetabled) - Written Unseen (50%)
    Assessment Methods & Exceptions Assessment:

    Exam (75%)
    Coursework (25%)

    Reassessment:

    Resubmission of failed assessment(s)
    Other None
    Reading List